Analysis of oromucosal medicinal products in solid dosage forms for therapeutic dentistry

L. I. Shulga, K. A. Chikhladze, S. M. Rolik, S. O. Povetkin

Abstract


In order to determine the necessity of creating dental medicinal products the oromucosal dosage forms of the Ukrainian pharmaceutical market have been analysed. Tablet drugs are increasingly used in the treatment of periodontal diseases. Based on the results of the analysis of 35 drugs it has been found that the share of drugs produced in Ukraine (23%) ranks second after Germany (31%) among manufacturer countries. According to the data of the marketing research 54.3% of solid dosage forms are tablets, 25.7% – lozenges and 20% – pastilles. It has been determined that 34.3% of drugs are two-component products, 25.7% – three-component, 20% are one-component and 20% are multi-component. Distinguishing the concept of active substances it has been shown that 77.1% of drugs contain antiseptics, 14.3% – antibiotics, 20% – essential oils, 17.1% – anesthetics. Natural substances as a component are in 8.6% of medicinal products, e.g. phenolic hydrophobic propolis preparation in “Proalor” (LLC “Pharmaceutical company “Zdorovie”, Ukraine), a thick sage extract in “Shavlia” (Natur Product Europa BV, Netherlands) and a solid chlorophyllipt extract in “Chlorophyllipt” tablets (LLC “Pilot Plant “State Scientific Centre on Medicinal Products”, Ukraine). It has been found that there is dominance of combined drugs and a small share of drugs based on natural substances; therefore, creation of oromucosal herbal medicinal products in a solid dosage form is expedient.

Keywords


dental medicinal products with the local action; solid dosage forms; marketing research; pharmaceutical market

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DOI: https://doi.org/10.24959/88846

Abbreviated key title: Vìsn. farm.

ISSN 2415-8844 (Online), ISSN 1562-7241 (Print)