The study of some pharmacognostic aspects of Ferula persica Wild. (Apiaceae) roots in the flora of Azerbaijan

Authors

DOI:

https://doi.org/10.24959/nphj.24.131

Keywords:

monoterpenes, sulfides, localization

Abstract

Aim. To determine the component composition of the monoterpene fraction of F. persica roots and identify the localization of biologically active substances in the raw material.

Materials and methods. The identification and quantitative analysis were performed using gas chromatography – mass spectrometry. The raw material was collected during the full seed ripening in the vicinity of the village Dzhangi in the Gobustan region of Azerbaijan.

Results and discussion. Using gas chromatography – mass spectrometry, 15 compounds of monoterpenes were identified. The predominant components were heneicosane – 5.10 %; tetradecane – 3.29 %; disulfide, bis(1-methylpropyl) – 2.86 %; heptadecane – 2.50 %; 9,12,15-octadecatrienoic acid 2,3-bis(acetyloxy)propyl ester – 2.39 %; thiophene, 2,3,4-trimethyl- – 2.05 % in the dry raw material. In addition, it was found that resin was localized in large schizogenous receptacles.

Conclusions. The content of monoterpenes in F. persica roots has been determined using gas chromatography – mass spectrometry. The roots contain monoterpenes of heneicosane; tetradecane; disulfide, bis(1-methylpropyl); heptadecane; 9,12,15-octadecatrienoic acid 2,3-bis(acetyloxy)propyl ester. Thiophene and 2,3,4-trimethyl predominate in the raw material.

Author Biographies

E. H. Kerimli , Azerbaijan Medical University; The Institute of Botany of Azerbaijan National Academy of Science

Candidate of Pharmacy (Ph.D.), senior lecturer of the Department of Pharmacognosy

Yu. B. Kerimov , Azerbaijan Medical University

Doctor of Pharmacy (Dr. habil.), professor, Honored Teacher, Scientific Consultant of the Department of Pharmacognosy

J. I. Isaev , Azerbaijan Medical University

Doctor of Pharmacy (Dr. habil.), professor, head of the Department of Pharmacognosy

P. V. Zulfugarova , The Institute of Botany of Azerbaijan National Academy of Science

Researcher at the Institute at the The Institute of Botany of Azerbaijan National Academy of Science

 

E. Yu. Akhmedov, National University of Pharmacy

Candidate of Pharmacy (Ph.D.), associate professor of the Department of General Chemistry

O. Yu. Maslov, National University of Pharmacy

Candidate of Pharmacy (Ph.D.), teaching assistant of the Department of General Chemistry

 

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Published

2024-03-20

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Vol. 107 No. 1 (2024)

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