Analysis of the range of medicines for the treatment of the wound process

Authors

DOI:

https://doi.org/10.24959/nphj.25.162%20

Keywords:

probiotics; market analysis; wound healing agents; pharmaceutical technology; dosage forms for external use

Abstract

Aim. To study the range of medicines that promote wound healing in the pharmaceutical market of Ukraine.

Materials and methods. The study objects were the State Register of Medicines, tabletki.ua website, patient information leaflets. Analytical and statistical methods of analysis were used in the study.

Results. After analyzing the market of wound-healing medicines, it has been found that according to the ATC classification, the group of medicines studied belongs to the ATC group D “Dermatological agents”. The study has found that 81.7 % of medicines are of domestic production, while 18.3 % are of foreign production. The most common are soft dosage forms – 50.4 %; the second position is occupied by liquid dosage forms – 48 %; the least drugs belong to solid dosage forms – 1.6 %.

Conclusions. After analyzing the entire range, it has been found that there are no probiotic medicines for local use in the pharmaceutical market. Therefore, there is a need for further research and development of wound-healing drugs with a probiotic effect for topical use.

Author Biographies

T. M. Mironchuk, Bogomolets National Medical University, Ukraine

Postgraduate student of the Department of Pharmacy and Industrial Technology of Drugs

Zh. M. Polova , Bogomolets National Medical University, Ukraine

Doctor of Pharmacy (Dr. habil.), professor, head of the Department of Pharmacy and Industrial Technology of Drugs

References

Abdi F. A., Motumma A. N., Kalayu A. A., & Abegaz W. E. (2024). Prevalence and antimicrobial-resistant patterns of Pseudomonas aeruginosa among burn patients attending Yekatit 12 Hospital Medical College in Addis Ababa, Ethiopia. PLoS One, 19(3), e0289586. https://doi.org/10.1371/journal.pone.0289586.

Liu Y. F., Ni P. W., Huang Y., & Xie T. (2022). Therapeutic strategies for chronic wound infection. Chin J Traumatol, 25(1), 11-16. https://doi.org/10.1016/j.cjtee.2021.07.004

Zu X., Han Y., Zhou W., Huangfu C., Zhang M., & Han Y. (2024). [Research progress of antibacterial hydrogel in treatment of infected wounds]. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, 38, 2, 249-255. https://doi.org/10.7507/1002-1892.202311003.

Bădăluță V. A., Curuțiu C., Dițu L. M., Holban A. M., & Lazăr V. (2024). Probiotics in Wound Healing. Int J Mol Sci, 25, 11, 5723. https://doi.org/10.3390/ijms25115723

Fijan S., Frauwallner A., Langerholc T., Krebs B., Ter Haar Née Younes J. A., Heschl A., Mičetić Turk D., & Rogelj I. (2019). Efficacy of Using Probiotics with Antagonistic Activity against Pathogens of Wound Infections: An Integrative Review of Literature. Biomed Res Int, 2019, https://doi.org/10.1155/2019/7585486

Tabletki.ua. https://tabletki.ua.

State Register of Medicinal Products. http://www.drlz.com.ua

Kompendium. Likarski preparaty. https://compendium.com.ua/uk

Polova, Zh. M. (2024). Study of the range of pharmaceutical market of probiotic-containing drugs with Bacillus, Lactobacillus and Bifidobacterium bacteria. Ukrainian Journal of Military Medicine, 5(2). 120-128.

Published

2025-03-21

Issue

Section

Articles