DOI: https://doi.org/10.24959/nphj.14.1936

Research of the assortment and merchandising analysis of anti epileptic drugs presented at the pharmaceutical market of Ukraine

T. V. Trunova

Abstract


According to the contemporary statistics, epilepsy is one of the most serious and widespread diseases of the nervous system. According to the WHO data epilepsy affects about 50 million people worldwide, in particular in Ukraine there are 500 000 patients with epilepsy, among them about 65% are children and adolescents. Adequate treatment of this pathology is one of the most difficult in clinical neurology and psychiatry. The research of the Ukrainian pharmaceutical market of anti-epileptic drugs has been conducted by the form of production and manufacturing countries; the need for these remedies at the social level has been determined. Consumer properties of drugs in the form of suppositories and their prospects in development of epilepsy treatment that will solve the problem of creating new, more effective and less toxic drugs for the treatment of this pathology have been analyzed. The greater part of drugs of this group is imported to Ukraine by foreign pharmaceutical companies. These circumstances lead to the fact that each year there are a lot of diverse studies for searching new potential anti-epileptic drugs. purposefulness of search generalizes all studies in this area both in case of creating analogues of the existing medicines, and in case of their possible metabolic products. In view of the above it can be concluded that the solution of the problem of creating new, more effective and less toxic drugs for the treatment of epilepsy is relevant and promising for medical and pharmaceutical science. Increase of the treatment efficiency and safety can only be done with the help of modern drugs.


Keywords


epilepsy; anti-epileptic drugs; dosage form; suppositories

Full Text:

PDF

References


Державний реєстр лікарських засобів [Електронний ресурс]. – Режим доступу: http://www.drlz.kiev.ua/

Козлова Н.Г., Романова Я.Ю., Замараева Е.Е., Долгая И.Н. // Фармаком. – 2005. – №2-3. – С. 25-30.

Компендіум 2011 – лікарські препарати / Під ред. В.Н.Коваленко, А.П.Вікторова. – К.: МОРІОН, 2011. – 2320 с.

Трунова Т.В., Штриголь С.Ю., Крутських Т.В. та ін. // Укр. біофармац. журн. – 2012. – №4 (21). – С. 25-28.

Цимбалюк В.І. // Здоров`я України. – 2003. – №81. – С. 34-35.

Эпилепсия [Электронный ресурс]. Всемирная организация здравоохранения. – Информационный бюлл. №999. – 2012. – Режим доступа: http://www.who.int/mediacentre/factsheets/fs999/ru/index.html

Anatomical Therapeutic Chemical Classification / WHO Collaborating Centre for Drug Statistics Methodology. − Oslo, 2007. − 48 p.

Brodie M.J. Anti-epileptic drugs: past, present and future / Ed. M.G.Brodie // Abstract Book 7th Asian & Oceanian Epilepsy Congress, China. – Hong Kong, 2008. – P. 3.

Hovinga C.A. // Exper. Opin. Invest. Drugs. – 2002. – Vol. 11, №10. – P. 1387-1406.

Kwan P., Brodie M.J. // Exp. Opеn. Emerging Drugs. − 2007. – Vol. 12, №3 – P. 407-422.

Scott R.A., Lhatoo S.D., Sander J.W. // Bull. World Health Organ. – 2001. – Vol. 79, №4. – Р. 344-351.

Semah F. // Epileptic Disord. – 2004. – Vol. 6, №4. – P. 255-265.

Sirven J.I., Sperling M., Wingerchuk D.M. // Cochrane Database of Systematic Rev. – 2001. – Vol. 3. – Р. 58.

Weaver D.F. // Can. J. Neurol. Sci. – 2003. – Vol. 30, №1. – P. 4-7.


GOST Style Citations






Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Abbreviated key title: Vìsn. farm.

ISSN 2415-8844 (Online), ISSN 1562-7241 (Print)