The quantitative content of the main groups of biologically active substances in the bay laurel raw materiaL

Authors

  • S. G. Musienko National University of Pharmacy, Ukraine
  • V. S. Kyslychenko National University of Pharmacy, Ukraine

DOI:

https://doi.org/10.24959/nphj.14.1998

Keywords:

biologically active substances, bay laurel, quantitative content

Abstract

The study of the chemical composition of the bay laurel raw material has shown that the plant raw material contains such groups of biologically active substances (BAS) as carbohydrates, fatty and amino acids, phenolic compounds revealing a wide spectrum of the biological activity. The data concerning the chemical composition of the bay laurel raw material is not enough described in the literature sources. The content of the main BAS in different samples of bay laurel shoots and leaves has been determined. The content of the total amount of organic acids, the total amount of oxidizable phenols, the total amount of hydroxycinnamic acids and the total amount of flavonoids in the bay laurel leaves samples are slightly higher. The content of the total amount of organic acids in shoots is not less than 1.7%, in leaves – not less than 1.9%. The content of the total amount of oxidizable phenols in both types of the raw material is not less than 4.5%, the total amount of hydroxycinnamic acids – not less than 1.3%, the total amount of flavonoids – not less than 0.8%. The standardization parameters for the bay laurel raw material have been determined on the basis of the research conducted. The results obtained will be used for developing the project of quality control methods “Lauri Cormus”.

References

Волошина А.А., Кисличенко В.С., Журавель І.О. та ін. // Укр. мед. альманах. – 2012. – Т. 15, №5. – С. 39-40.

Государственная фармакопея СССР. Вып. 2. Общие методы анализа. Лекарственное растительное сырье / МЗ СССР. – 11-е изд. – М.: Медицина, 1989. – 400 с.

Пилипенко Ф.С. / Под ред. С.Я.Соколова. – М. – Л.: Изд-во АН СССР, 1954. – Т. III. Покрытосеменные. Семейства Троходендроновые – Розоцветные. – С. 122-123.

Ben Jemaa J.M., Tersim N., Toudert K.T. et al. // J. Stored Prod. Res. – 2012. – Vol. 48. – Р. 97-104.

Bilen S., Bulut M. // J. of Animal and Veterinary Advances. – 2010. – Vol. 9 (8). – P. 1275-1277.

Dall’Acqua S., Cervellati R., Speroni E. et al. // J. of Medicinal Food. – 2009. – №12. – Р. 869-876.

Derwich E., Benziane Z., Boukir A. // Aust. J. Basic. Appl. Sci. – 2009. – №3. – Р. 3818-3824.

Dias M.I., Barros L., Dueñas M. et al. // Food Chemistry. – 2013. – Vol. 141. – P. 869-872.

Emam A.M., Mohamed M.A., Diab Y.M. et al. // Drug Discoveries and Therapeutics. – 2010. – Vol. 4 (3). – P. 202-207.

Esra K., Ilkay O., Erdem Y. // Pharmac. Biol. – 2007. – Vol. 45, Issue 7. – P. 547-555.

Ham A., Shin J., Oh K. et al. // Biomol. Ther. – 2011. – Vol. 19, Issue 1. – P. 118-125.

Marzouki H., Piras A., Marongiu B. et al. // Molecules. – 2008. – Vol. 13. – P. 1702-1711.

Ozcan B., Esen M., Sangun M.K. et al. // J. Environ. Biol. – 2010. – Vol. 31. – P. 637-641.

Ramling P., Meera M., Priyanka P. // Int. J. of Pharm. and Chem. Sci. – 2012. – Vol. 1 (2). – P. 595-602.

Rizi M.V. // Iranian J. of Pharmac. Sci. – 2009. – Vol. 5, Issue 1. – P. 47-50.

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Published

2014-12-01

Issue

Section

Synthesis and Analysis of Biologically Active Substances