Branched-chain amino acids: market analysis, use and prospects for creating domestic dietary supplements

Authors

DOI:

https://doi.org/10.24959/nphj.25.186

Keywords:

branched-chain amino acids, BCAAs, dietary supplement, supplements to athletes' diets, bioavailability, encapsulation

Abstract

Branched-chain amino acids (BCAA) are key to the muscle metabolism, recovery, and energy supply, making them in demand in sports nutrition and medicine. The BCAA encapsulation increases their stability and bioavailability. The relevance of creating domestic competitive dietary supplements with BCAA is due to the growing demand and promising use for medical and sports practice.

Aim. To study the current state of the use of branched-chain amino acids in the world and Ukraine, analyze market trends, market segmentation by type and form of BCAA-based products and the encapsulation technology in order to substantiate the prospects for creating domestic competitive dietary supplements for sports, medical practice and health maintenance.

Materials and methods. The study used the bibliosemantic method of analyzing information from scientific publications, which is combined with other research methods, such as the comparative, logical, marketing and content analysis. The BCAA market review was conducted using data from analytical reports and research available online. The assortment analysis of BCAA-based products was conducted using data from open sources, in particular, official websites of manufacturers and market places. The information was searched using the following keywords: branched-chain amino acids, BCAA, health effects, dietary supplement, supplements to the diet of athletes, bioavailability, encapsulation, etc. in the Google search engine.

Results. The analysis of scientific literature data has shown that BCAAs are important biologically active substances that are widely used in sports practice, medicine and pharmacy. Leucine, isoleucine and valine affect glucose metabolism, immunity, lipolysis, cardiometabolic health and cancer processes. They are effective in sports nutrition, muscle recovery, prevention of diabetes, cardiovascular diseases, and immune support. The physiological and metabolic properties of BCAAs have been analyzed, which prove their prospects for use as dietary supplements. It has been found that the BCAA market in the world has stable growth with a projected total annual growth rate of at least 3.5 %. Data on the structure of the product market by type and ratio of amino acids, by the share of products for sports practice are presented. The main trends of the BCAA product market in Ukraine and the world have been identified. The release forms of BCAA products for sports practice have been analyzed. It has been found that the largest share is represented by dosage forms in the form of powders. Aspects of the encapsulation technology have been considered, and its prospects for creating a dietary supplement with BCAAs have been substantiated.

Conclusions. These studies open up prospects for expanding the range of products containing BCAAs, in particular by creating dietary supplements intended for use in sports practice and maintaining the health of a wide range of consumers.

Author Biographies

N. V. Dvinskykh, National University of Pharmacy of the Ministry of Health of Ukraine, Kharkiv

Candidate of Pharmacy, Senior Researcher, associate professor of the Department of Biotechnology

N. V. Khokhlenkova, National University of Pharmacy of the Ministry of Health of Ukraine, Kharkiv

Doctor of Pharmacy, professor, head of the Department of Biotechnology

O. S. Kaliuzhnaia, National University of Pharmacy of the Ministry of Health of Ukraine, Kharkiv

Candidate of Pharmacy, associate professor of the Department of Biotechnology

O. V. Filiptsova, National University of Pharmacy of the Ministry of Health of Ukraine, Kharkiv

Doctor of Biology (Dr. habil.), professor of the Department of Biotechnology

References

Yu, S., Zheng, B., Chen, Z., & Huo, Yi-Xin. (2021). Metabolic engineering of Corynebacterium glutamicum for producing branched chain amino acids. Microbial Cell Factories, 20(1), 230. http://doi.org/10.1186/s12934-021-01721-0

Branched Chain Amino Acids Market Size, Forecasts Report 2032. Global Market Insights Inc. https://www.gminsights.com/industry-analysis/branched-chain-amino-acids-market

Hao, Y., Pan, X., You, J., Li, G., Xu, M., & Rao, Z. (2024). Microbial production of branched chain amino acids: Advances and perspectives. Bioresource Technology, 397, 130502. https://doi.org/10.1016/j.biortech.2024.130502

Reifenberg, P., & Zimmer, A. (2024). Branched-chain amino acids: physico-chemical properties, industrial synthesis and role in signaling, metabolism and energy production. Amino Acids, 56(51), 1–27. https://doi.org/10.1007/s00726-024-03417-2

Zhang, S., Zeng, X., Ren, M., Mao, X., & Qiao, S. (2017). Novel metabolic and physiological functions of branched chain amino acids: a review. J. Animal Sci. Biotechnol., 23(8), 10. https://doi.org/10.1186/s40104-016-0139-z

Xu, E., Ji, B., Jin, K., & Chen, Y. (2023). Branched-chain amino acids catabolism and cancer progression: focus on therapeutic interventions. Frontiers in Oncology, 10(13), 1220638. https://doi.org/ 10.3389/fonc.2023.1220638

Nie, C., He, T., Zhang, W., Zhang, G., & Ma, X. (2018). Branched Chain Amino Acids: Beyond Nutrition Metabolism. Int. J. Mol. Sci., 19(4), 954. http://doi.org/10.3390/ijms19040954

Agrawal, A., Maharana, J. K., Mohanty, A., & Patel, A. K. (2024). Microbial Production of Amino Acids and Their Applications in Health and Nutrition Sectors. In V. Kothari, S. Ray, & P. Kumar (Eds.), Microbial Products for Health and Nutrition (p. 305–313). Springer. https://doi.org/10.1007/978-981-97-4235-6_13

BCAA market size, share, growth, and industry analysis, by type (2:1:1 and others), by application (sports nutrition, pharmaceutical, and others), regional insights and forecast from 2025 to 2034. (2025, October 13). Business Research Insights. https://www.businessresearchinsights.com/market-reports/bcaa-market-100303

Branch chain amino acid (BCAA) market size, share, and growth analysis. (2024, December). SkyQuest Technology https://www.skyquestt.com/report/branch-chain-amino-acid-market

Global branched-chain amino acids market size, share, trends growth forecast report by type, application, and region (North America, Europe, Asia-Pacific, Latin America, Middle East and Africa), industry analysis from 2025 to 2033. (2025, March). Market Data Forecast. https://www.marketdataforecast.com/market-reports/branched-chain-amino-acids-market

BCAA market: Segments – by product form (powder, capsule, tablet, liquid), application (sports nutrition, dietary supplements, pharmaceuticals, animal feed, and others), distribution channel (online stores, supermarkets/hypermarkets, specialty stores, and others), end-user (athletes, bodybuilders, general population, and others), and region (Asia Pacific, North America, Latin America, Europe, and Middle East & Africa) – global industry analysis, growth, share, size, trends, and forecast 2025–2033. (2024, September 23). DataIntelo. https://dataintelo.com/report/global-bcaa-market

Branched chain amino acid (BCAA) market. (2025, October 29). Custom Market Insights. https://www.custommarketinsights.com/report/branched-chain-amino-acid-bcaa-market/

Global BCAA market size, manufacturers, supply chain, sales channel and clients, 2025–2031. (2025, May). Valuates Reports. https://reports.valuates.com/market-reports/QYRE-Auto-23P11858/global-bcaa

BCAA supplements market 2025–2032 revolutionary insights into trends, dynamics, growth, future challenges, strategies. (2025, March 6). Orion Market Research. https://www.openpr.com/news/3901533/bcaa-supplements-market-2025-2032-revolutionary-insights-into

BCAA. Shcho tse za aminokysloty, dlia choho BCAA i yak yikh pryimaty. Belok. https://belok.ua/ua/blog/bcaa-chto-eto-za-aminokisloty-dlya-chego-bcaa-i-kak-ih-prinimat/

BCAA. GymBeam dlia kozhnoho vydu sporta. http://surl.li/ullule

Sportyvne kharchuvannia. Mordex. Vse dlia Fitnesu ta Bodybildynhu. https://mordex.net/ua/sportivnoe-pitanie/

BCAA. Sport Havka. http://surl.li/wrewvp

Slow Release BCAA. Natural Vitamin E, Micro-Encapsulated Powders, Phytosterol Ester, Fat Soluble Vitamins, Omega-3. Powder Factory, Supplier and Producer – Xi’an Healthful Biotechnology. https://www.hsfbiotech.com/solipro-micro-encaplated-solid-powder/sustained-release-bcaa.html

Horiuk, P. I., & Hakman, A. V. (2018). Osnovy sportyvnoho kharchuvannia: navch.-metod. posib. Chernivetskyi natsionalnyi universytet.

Chkhailo, M. B. (2023). Perspektyvy vykorystannia diietychnykh dobavok u sportyvnii praktytsi. Olimpiiskyi ta paralimpiiskyi sport, (1), 33–37.

Prytulska, N. V., & Koshelnyk, A. V. (2017). Analiz asortymentu diietychnykh dobavok dlia vidnovlennia sportsmeniv. In Merezhevyi biznes: stanovlennia, problemy, innovatsii (p. 48–51). Poltavskyi universytet ekonomiky i torhivli.

Ponomarov, V. O., Tsarenko, K. V., & Bulakh, S. M. (2024). Sportyvno-pedahohichne vdoskonalennia: metod. rek. do samostiinoi roboty dlia zdobuvachiv stupenia vyshchoi osvity bakalavra spets. «Fizychna kultura i sport» osvitno-profesiinoi prohramy «Sport». Zaporizkyi natsionalnyi universytet.

Prytulska, N. V., & Koshelnyk, A. V. (2018). Asortymentna polityka vyrobnykiv sportyvnoho kharchuvannia v Ukraini ta sviti. Visnyk LTEU. Tekhnichni nauky, (20), 41–47.

Zakon Ukrainy «Pro vnesennia zmin do deiakykh zakoniv Ukrainy shchodo udoskonalennia rehuliuvannia vyrobnytstva ta obihu diietychnykh dobavok, vrehuliuvannia inshykh pytan u sferi okhorony zdorovia» № 4122-IX (2024, Hruden 5). Vidomosti Verkhovnoi Rady Ukrainy, (19), 64. https://zakon.rada.gov.ua/laws/show/4122-20#Text

Derzhavne pidpryiemstvo «Ukrainskyi naukovyi farmakopeinyi tsentr yakosti likarskykh zasobiv». (2020). Derzhavna Farmakopeia Ukrainy. Dopovnennia 4 (2-he vyd.). Derzhavne pidpryiemstvo «Ukrainskyi naukovyi farmakopeinyi tsentr yakosti likarskykh zasobiv».

Nakaz MOZ Ukrainy «Pro zatverdzhennia Hihiienichnykh vymoh do diietychnykh dobavok» № 1114 (2013, Hruden 19). Ofitsiinyi vebportal prlamentu Ukrainy. https://zakon.rada.gov.ua/laws/show/z2231-13#Text

Sakhno, T. V., Irhibaieva, I. S., & Barashkov, M. M. (2022). Doslidzhennia biorozkladnykh polimeriv dlia vykorystannia v molochnii ta kharchovii promyslovosti. In Innovatsiini aspekty system bezpeky pratsi, zakhystu intelektualnoi vlasnosti (p. 98–101). Poltavskyi derzhavnyi ahrarnyi universytet. https://repository.pdmu.edu.ua/handle/123456789/20166

Inkapsuliatory. Donau Lab Ukraine. https://dlu.com.ua/Інкапсулятори

Gruskiene, R., Bockuviene, A., & Sereikaite, J. (2021). Microencapsulation of Bioactive Ingredients for Their Delivery into Fermented Milk Products: A Review. Molecules, 26(15), 4601. https://doi.org/10.3390/molecules26154601

Shishir, M. R. I., Xie, L., Sun, Ch., Zheng, X., & Chen, W. (2018). Advances in micro and nano-encapsulation of bioactive compounds using biopolymer and lipid-based transporters. Trends in Food Science Technology, 78, 34–60. https://doi.org/10.1016/j.tifs.2018.05.018

Published

2026-01-16

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Articles