The study of saponins of the raspberry cake alcoholic extract by HPLC

Authors

DOI:

https://doi.org/10.24959/nphj.18.2230

Keywords:

малина обыкновенная, ВЭЖХ, екстракт, сапонины

Abstract

Aim. To study saponins of the raspberry cake ethanol extract.

Materials and methods. The object of the study was the extract obtained from the cake of Rubus idaeus fruit. The study of saponin compounds was carried out by HPLC.

Results and discussion. The following saponins were found in the extract: euscapic acid (0.24 %), tormentic acid (0.14 %), lupeol (0.65 %). These compounds are of interest to pharmacy and medicine as substances with the oncoprotective and hepatoprotective activity.

Conclusions. The qualitative and quantitative composition of saponins in the cake extract of raspberry fruits has been studied. The results indicate the prospects of creating new drugs based on biologically active substances of the raspberry fruit cake, as well as necessity of more profound study of phenolic compounds of this type of the raw material.

Author Biographies

I. M. Polishchuk, National university of pharmacy

postgraduate student of the Department of Chemistry of Natural Compounds

M. A. Komisarenko, National university of pharmacy

Candidate of Pharmacy (Ph.D), teaching assistant of the Pharmacognosy Department

M. Yu. Golik, National university of pharmacy

Candidate of Chemistry (Ph.D), associate professor of the Analytical Chemistry Department

T. V. Upyr, National university of pharmacy

Candidate of Pharmacy (Ph.D), teaching assistant of the Pharmacognosy Department

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Published

2018-11-29

Issue

No. 4(96) (2018)

Section

Synthesis and Analysis of Biologically Active Substances

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